Autoimmune Diseases as Stem Cell Disorders.

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Autoimmune diseases as stem cell disorders.

Using an animal model for insulin-dependent diabetes mellitus (IDDM), the NOD mouse, we have demonstrated that allogeneic bone marrow transplantation (BMT) has a preventative effect on IDDM, and that a combined transplantation of pancreas and bone marrow can be used to treat IDDM. We have also shown that BMT has a curative effect on systemic autoimmune disease in (NZB x NZW) F1, BXSB, and (NZW ...

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ژورنال

عنوان ژورنال: The Tohoku Journal of Experimental Medicine

سال: 1994

ISSN: 0040-8727,1349-3329

DOI: 10.1620/tjem.173.141